HIV Mutation Detail Information

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Mutation Information
Mutation Site E157Q
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Viral Reference K03455.1
Relevant Drug INSTIs
Country Russia
Literature Information
PubMed PMID 32752001
Disease HIV infection/AIDS
Published Year 2020
Journal Viruses
Title Genetic Features of HIV-1 Integrase Sub-Subtype A6 Predominant in Russia and Predicted Susceptibility to INSTIs.
Author Kirichenko A,Lapovok I,Baryshev P,van de Vijver DAMC,van Kampen JJA,Boucher CAB,Paraskevis D,Kireev D
Evidence Additionally, 3 INSTI-naive patients had accessory mutations: E157Q (2/183;1.1%) and T97A (1/183;0.5%), which alone have minimal impact on INSTI susceptibility or HIV-1 replication capacity.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation