|
Mutation Information
|
Mutation Site
|
E157Q |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Genotype/Subtype
|
RFCD;D;C |
|
Relevant Drug
|
INSTIs |
|
Country
|
Tanzania |
Literature Information
|
PubMed PMID
|
32126792
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
AIDS research and human retroviruses |
|
Title
|
Circulating HIV-1 Integrase Genotypes in Tanzania: Implication on the Introduction of Integrase Inhibitors-Based Antiretroviral Therapy Regimen. |
|
Author
|
Masoud S,Kamori D,Barabona G,Mahiti M,Sunguya B,Lyamuya E,Ueno T |
|
Evidence
|
No major INSTI resistance mutations were found;however, accessory resistance mutations at positions T97A, E157Q, G163E/K, and 128A/T were detected in 5% of subjects.
|
|
|
HIV Mutation Detail Information