|
Mutation Information
|
Mutation Site
|
E157Q |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Viral Reference
|
K03455.1
|
|
Country
|
Nigeria |
Literature Information
|
PubMed PMID
|
32105319
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
The Journal of antimicrobial chemotherapy |
|
Title
|
High prevalence of integrase mutation L74I in West African HIV-1 subtypes prior to integrase inhibitor treatment. |
|
Author
|
El Bouzidi K,Kemp SA,Datir RP,Murtala-Ibrahim F,Aliyu A,Kwaghe V,Frampton D,Roy S,Breuer J,Sabin CA,Ogbanufe O,Charurat ME,Bonsall D,Golubchik T,Fraser C,Dakum P,Ndembi N,Gupta RK |
|
Evidence
|
The most common integrase polymorphism was E157Q, which was detected in 12 participants (6 of these also had L74I).
|
|
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HIV Mutation Detail Information