|
Mutation Information
|
Mutation Site
|
E157Q |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
raltegravir (RAL) |
|
Country
|
Germany |
Literature Information
|
PubMed PMID
|
25397491
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
|
Journal
|
Journal of the International AIDS Society |
|
Title
|
Characterization of natural polymorphic sites of the HIV-1 integrase before the introduction of HIV-1 integrase inhibitors in Germany. |
|
Author
|
Meixenberger K,Yousef KP,Somogyi S,Fiedler S,Bartmeyer B,von Kleist M,Kücherer C |
|
Evidence
|
E157Q considered by HIVdb, ANRS, and GRADE algorithms was the most frequent resistance-associated polymorphism with an overall prevalence of 2.4%.
|
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HIV Mutation Detail Information