|
Mutation Information
|
Mutation Site
|
E138K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
Literature Information
|
PubMed PMID
|
33979774
|
|
Published Year
|
2021 |
|
Journal
|
Bioorganic & medicinal chemistry |
|
Title
|
Design, synthesis and anti-HIV evaluation of novel 5-substituted diarylpyrimidine derivatives as potent HIV-1 NNRTIs. |
|
Author
|
Gao P,Song S,Wang Z,Sun L,Zhang J,Pannecouque C,De Clercq E,Zhan P,Liu X |
|
Evidence
|
What's more, some compounds also showed low nanomole activity against some mutant strains such as K103N and E138K.
|
|
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HIV Mutation Detail Information