HIV Mutation Detail Information

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Mutation Information
Mutation Site E138K
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Literature Information
PubMed PMID 33979774
Published Year 2021
Journal Bioorganic & medicinal chemistry
Title Design, synthesis and anti-HIV evaluation of novel 5-substituted diarylpyrimidine derivatives as potent HIV-1 NNRTIs.
Author Gao P,Song S,Wang Z,Sun L,Zhang J,Pannecouque C,De Clercq E,Zhan P,Liu X
Evidence What's more, some compounds also showed low nanomole activity against some mutant strains such as K103N and E138K.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation