HIV Mutation Detail Information

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Mutation Information
Mutation Site E138K
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Genotype/Subtype D
Viral Reference HXB2
Relevant Drug INSTIs
Country Uganda
Literature Information
PubMed PMID 33635845
Disease HIV infection/AIDS
Published Year 2021
Journal AIDS (London, England)
Title Pre-treatment integrase inhibitor resistance is uncommon in antiretroviral therapy-naive individuals with HIV-1 subtype A1 and D infections in Uganda.
Author McCluskey SM,Kamelian K,Musinguzi N,Kigozi S,Boum Y 2nd,Bwana MB,Muzoora C,Brumme ZL,Carrington M,Carlson J,Foley B,Hunt PW,Martin JN,Bangsberg DR,Harrigan PR,Siedner MJ,Haberer JE,Lee GQ
Evidence Of these, two had E138T (subtype A1), three had E138E/K (subtype D), and one had T66T/I (subtype D).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation