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Mutation Information
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Mutation Site
|
E138K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B;C;BF;AE |
|
Viral Reference
|
K03455.1
|
|
Country
|
UK;Germany;Spain;France;Belgium;Greece;South Africa;Uganda;Brazil;Argentina;Peru;USA;Thailand;India;Australia. |
Literature Information
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PubMed PMID
|
33369017
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2021 |
|
Journal
|
HIV medicine |
|
Title
|
Transmitted HIV-1 drug resistance in a large international cohort using next-generation sequencing: results from the Strategic Timing of Antiretroviral Treatment (START) study. |
|
Author
|
Baxter JD,Dunn D,Tostevin A,Marvig RL,Bennedbaek M,Cozzi-Lepri A,Sharma S,Kozal MJ,Gompels M,Pinto AN,Lundgren J,INSIGHT START Study Group. |
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Evidence
|
TDR was based on the WHO 2009 surveillance definition with the addition of reverse transcriptase (RT) mutations T215N and E138K, and integrase strand transfer inhibitor (INSTI) surveillance mutations (Stanford HIVdb).
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HIV Mutation Detail Information