HIV Mutation Detail Information

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Mutation Information
Mutation Site E138K
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Genotype/Subtype A
Relevant Drug INSTIs
Country Cameroon
Literature Information
PubMed PMID 32954411
Disease HIV infection/AIDS
Published Year 2021
Journal The Journal of antimicrobial chemotherapy
Title Prevalence of integrase strand transfer inhibitor resistance mutations in antiretroviral-naive HIV-1-infected individuals in Cameroon.
Author Wenk BM,Mbunkah HA,Nsanwe NN,Mbu ET,Besong LM,Sama BA,Orock E,Leemann C,Metzner KJ
Evidence At low abundance (frequency between 3% and 15%), 3/255 (1.2%) individuals each harboured one major INSTI DRM: E138K (4.4%), G140S (5.7%) and Y143C (9.0%) (Table 2).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation