Mutation Information
Mutation Site
|
E138G |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NRTIs |
Country
|
Spain |
Literature Information
PubMed PMID
|
32030406
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
The Journal of antimicrobial chemotherapy |
Title
|
The algorithm used for the interpretation of doravirine transmitted drug resistance strongly influences clinical practice and guideline recommendations. |
Author
|
Guerrero-Beltrán C,Martínez-Sanz J,Álvarez M,Olalla J,García-Álvarez M,Iribarren JA,Masiá M,Montero M,García-Bujalance S,Blanco JR,Rivero M,García-Fraile LJ,Espinosa N,Rodríguez C,Aguilera A,Vidal-Ampurdanes MC,Martínez M,Iborra A,Imaz A,Gómez-Sirvent JL,Peraire J,Portilla J,Caballero E,Alejos B,García F,Moreno S,CoRIS. |
Evidence
|
METHODS: We used the WHO 2009 list to investigate the prevalence of NNRTI, NRTI and PI TDR, in treatment-naive HIV-1-infected patients, adding mutations E138A/G/K/Q/R, V106I, V108I, V179L, G190Q, H221Y, F227C/L/V, M230IDR, L234I, P236L and Y318F in RT.
|
|
|