HIV Mutation Detail Information

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Mutation Information

Mutation Site	E138A
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NNRTIs
Country	Kenya;uganda

Literature Information

PubMed PMID	33561143
Disease	HIV infection/AIDS
Published Year	2021
Journal	PLoS medicine
Title	HIV incidence after pre-exposure prophylaxis initiation among women and men at elevated HIV risk: A population-based study in rural Kenya and Uganda.
Author	Koss CA,Havlir DV,Ayieko J,Kwarisiima D,Kabami J,Chamie G,Atukunda M,Mwinike Y,Mwangwa F,Owaraganise A,Peng J,Olilo W,Snyman K,Awuonda B,Clark TD,Black D,Nugent J,Brown LB,Marquez C,Okochi H,Zhang K,Camlin CS,Jain V,Gandhi M,Cohen CR,Bukusi EA,Charlebois ED,Petersen ML,Kamya MR,Balzer LB
Evidence	One participant had mutations in reverse transcriptase (K103N, E138A) likely due to transmitted drug resistance to non-nucleoside reverse transcriptase inhibitors (NNRTI) not related to PrEP use.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation