HIV Mutation Detail Information

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Mutation Information

Mutation Site	E138A
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	CRF02_AG;G
Viral Reference	K03455.1
Relevant Drug	NNRTIs
Country	Cameroon

Literature Information

PubMed PMID	32692778
Disease	HIV infection/AIDS
Published Year	2020
Journal	PloS one
Title	Pre-treatment drug resistance and HIV-1 genetic diversity in the rural and urban settings of Northwest-Cameroon.
Author	Fokam J,Takou D,Teto G,Nforbih SE,Kome OP,Santoro MM,Ngoufack ES,Eyongetah M,Palmer D,Fokunang ET,Fokunang CN,Colizzi V,Perno CF,Ndjolo A
Evidence	Fifteen (15) PDR mutations were found among four patients the urban settings [6 resistance mutations to NRTIs:[M41L (2), E44D (1), K65R (1), K70E (1), M184V/I (2), K219R (1)] and 6 resistance mutations to NNRTIs: K103N (1), E138A/G (2), V179E (1), M230L (1), K238T (1), P225H (1)] against two (02) mutations found in two patients in the rural setting[2 resistant mutations to NNRTIs: E138A (1) and Y188H (1)].

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation