Mutation Information
Mutation Site
|
E138A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NRTIs |
Country
|
America |
Literature Information
PubMed PMID
|
29846534
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2019 |
Journal
|
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America |
Title
|
Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted Human Immunodeficiency Virus Type 1 Drug Resistance in a Large US Clinic Population. |
Author
|
Rhee SY,Clutter D,Fessel WJ,Klein D,Slome S,Pinsky BA,Marcus JL,Hurley L,Silverberg MJ,Kosakovsky Pond SL,Shafer RW |
Evidence
|
The mutations E138A/G/K/Q, which are associated with reduced RPV susceptibility but are not on the SDRM list, occurred in 99 individuals, including 90 without an SDRM.
|
|
|