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Mutation Information
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Mutation Site
|
E138A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
Nicaragua |
Literature Information
|
PubMed PMID
|
27736898
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2016 |
|
Journal
|
PloS one |
|
Title
|
HIV Drug Resistance in Antiretroviral Treatment-Naïve Individuals in the Largest Public Hospital in Nicaragua, 2011-2015. |
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Author
|
Avila-Ríos S,García-Morales C,Matías-Florentino M,Tapia-Trejo D,Hernández-Álvarez BF,Moreira-López SE,Quant-Durán CJ,Porras-Cortés G,Reyes-Terán G |
|
Evidence
|
This increase was mainly NNRTI-associated due to the presence of the polymorphic mutation E138A (86% of cases) and to a lesser extent V108I (14% of cases), which are not considered in the SDRMs list.
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HIV Mutation Detail Information