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Mutation Information
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Mutation Site
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E109D |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
L2 |
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Amino acid_Mutation
|
G4461C |
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Genotype/Subtype
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HPV51 |
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Viral Reference
|
M62877
|
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Country
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China |
Literature Information
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PubMed PMID
|
30583025
|
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Disease
|
HPV infection
|
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Published Year
|
2019 |
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Journal
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Gene |
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Title
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Genetic variability of human papillomavirus type 51 E6, E7, L1 and L2 genes in Southwest China. |
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Author
|
Xu J,Tan L,Wang T,Cui F,Ding X,Wan Q,Deng D,Chen Z |
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Evidence
|
Besides, the non-synonymous mutations G4227A (V32I), A4407G (I92V), G4945A (D271N), C4985A (T284K), T5260G (L376V), A5335C (T401P) and the synonymous mutations A4166G, G4229A, G4283A, T4453C, C4566A, T4596C, C4695T, C4830T, G4839A, A5160C, and T5286G were the most common mutations. Specially, a triallelic mutation site (G4461C/A) in L2 was identified, with 26% G4461C (E109D) being non-synonymous mutation.
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HPV Mutation Detail Information