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Mutation Information
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Mutation Site
|
D99N |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
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Genotype/Subtype
|
C |
|
Country
|
China |
Literature Information
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PubMed PMID
|
22500577
|
|
Disease
|
HBV infection
|
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Published Year
|
2012 |
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Journal
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Virology journal |
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Title
|
Hepatitis B surface antigen variants in voluntary blood donors in Nanjing, China. |
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Author
|
Yong-Lin Y,Qiang F,Ming-Shun Z,Jie C,Gui-Ming M,Zu-Hu H,Xu-Bing C |
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Evidence
|
Besides G145R, there were different types of aa substitutions in the MHR that were associated with lower reactivity in HBsAg assays reported in previous studies: i.e. D99N, Q101R/H, L109I, I110N, T115S, S117T, P120S, K122R, S126T/A, P127H, A128V, Q129R/H/L, G130E, T131N/A, M133T/L/S, F134R/I/L, T143M, A159V, F161Y, W163G, E164G, V168A.
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HBV Mutation Detail Information