HPV Mutation Detail Information

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Mutation Information

Mutation Site	D86E
Mutation Type	Amino acid level
Gene/Protein/Region Type	E6
Genotype/Subtype	HPV58
Viral Reference	D90400.1
Country	French Guiana

Literature Information

PubMed PMID	33238632
Disease	High grade squamous intraepithelial lesion; Low grade squamous intraepithelial lesion
Published Year	2020
Journal	Microorganisms
Title	E6/E7 Sequence Diversity of High-Risk Human Papillomaviruses in Two Geographically Isolated Populations of French Guiana.
Author	Nacher M,Godefroy G,Dufit V,Douine M,Najioullah F,Césaire R,Thomas N,Drak Alsibai K,Adenis A,Lacoste V
Evidence	The last two were a Brazilian woman from Saint Georges and a Surinamese woman from Papaichton. The E6 sequences presented two nucleotide substitutions at positions 78 and 258, one of which was nonsynonymous leading to the D86E mutation (relative to the reference sequence, accession # D90400).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation