Mutation Information
Mutation Site
|
D67N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
tenofovir (TFV) |
Country
|
South Africa |
Literature Information
PubMed PMID
|
31143879
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2019 |
Journal
|
EClinicalMedicine |
Title
|
Trends in Pretreatment HIV-1 Drug Resistance in Antiretroviral Therapy-naive Adults in South Africa, 2000-2016: A Pooled Sequence Analysis. |
Author
|
Chimukangara B,Lessells RJ,Rhee SY,Giandhari J,Kharsany ABM,Naidoo K,Lewis L,Cawood C,Khanyile D,Ayalew KA,Diallo K,Samuel R,Hunt G,Vandormael A,Stray-Pedersen B,Gordon M,Makadzange T,Kiepiela P,Ramjee G,Ledwaba J,Kalimashe M,Morris L,Parikh UM,Mellors JW,Shafer RW,Katzenstein D,Moodley P,Gupta RK,Pillay D,Abdool Karim SS,de Oliveira T |
Evidence
|
Classical TAMs (M41L, D67N, K70R, L210W, T215FY, and K219EQ) were detected in 36 sequences (7.5% of sequences with any DRM;0.5% of all sequences).
|
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