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Mutation Information
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Mutation Site
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D67N |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Combined Mutation
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rt.K219E+rt.K219Q+rt.D67N;rt.K219E+rt.K219Q+rt.T215rev+rt.D67N;rt.K219E+rt.T215F+rt.D67N |
Literature Information
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PubMed PMID
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30544247
|
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Disease
|
HIV infection/AIDS
|
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Published Year
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2019 |
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Journal
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The Journal of antimicrobial chemotherapy |
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Title
|
Virological outcomes of boosted protease inhibitor-based first-line ART in subjects harbouring thymidine analogue-associated mutations as the sole form of transmitted drug resistance. |
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Author
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Geretti AM,White E,Orkin C,Tostevin A,Tilston P,Chadwick D,Leen C,Sabin C,Dunn DT,UK HIV Drug Resistance Database and UK CHIC Study. |
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Evidence
|
TAMs comprised the RT mutations M41L, D67N/G/E, K70R, L210W, T215Y/F/rev and K219Q/E/N/R; T215rev comprised any change from T215 other than T215Y and T215F.
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HIV Mutation Detail Information