HIV Mutation Detail Information

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Mutation Information
Mutation Site D67N
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Country Thailand
Literature Information
PubMed PMID 22132100
Disease HIV infection/AIDS
Published Year 2011
Journal PloS one
Title Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis.
Author Ngo-Giang-Huong N,Jourdain G,Amzal B,Sang-a-gad P,Lertkoonalak R,Eiamsirikit N,Tansuphasawasdikul S,Buranawanitchakorn Y,Yutthakasemsunt N,Mekviwattanawong S,McIntosh K,Lallemant M,Program for HIV Prevention and Treatment (PHPT) study group.
Evidence Longer duration of virologic failure was found significantly associated with higher risk of all TAM-2 mutations (D67N, K70R, K219Q/E, T215F) and the T215Y mutation with ORs ranging from 1.25 to 1.84 and PP[OR>1]>98% (Figure 2D).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation