HIV Mutation Detail Information

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Mutation Information

Mutation Site	D67N
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.D67N+rt.K70R
Relevant Drug	zidovudine (ZDV) ;didanosine (DDI);lopinavir(LPV);ritonavir
Country	South Africa

Literature Information

PubMed PMID	21694608
Disease	HIV infection/AIDS
Published Year	2011
Journal	Journal of acquired immune deficiency syndromes (1999)
Title	Genotypic resistance at viral rebound among patients who received lopinavir/ritonavir-based or efavirenz-based first antiretroviral therapy in South Africa.
Author	Dlamini JN,Hu Z,Ledwaba J,Morris L,Maldarelli FM,Dewar RL,Highbarger HC,Somaroo H,Sangweni P,Follmann DA,Pau AK,Phidisa II Study Team.
Evidence	Four participants had at least one thymidine-associated mutation (TAM) – two recipients of ZDV+ddI had D67N + K70R, another ZDV+ddI recipient had K70R alone.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation