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Mutation Information
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Mutation Site
|
D63E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
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Genotype/Subtype
|
HPV16 |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
15363193
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2004 |
|
Journal
|
Ai zheng = Aizheng = Chinese journal of cancer |
|
Title
|
[Analysis of human papillomavirus 16 E6 oncogene mutation in Xinjiang Uygur women with cervical carcinoma]. |
|
Author
|
Ma ZH,Zhang FC,Mei XD,Ma CL,Liu KJ |
|
Evidence
|
The result of PCR showed that the positive rate of HPV16E6 was 82.86%(29/35); 26 of these 29 PCR fragments were sequenced and analyzed, 15 of them maintained prototype (57.69%), 11 have L83V mutation (34.62%), and 2 have L83V/D63E mutation (7.69%).
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HPV Mutation Detail Information