Mutation Information
Mutation Site
|
D60E |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Literature Information
PubMed PMID
|
31409143
|
Published Year
|
2019 |
Journal
|
Journal of enzyme inhibition and medicinal chemistry |
Title
|
Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease. |
Author
|
Maseko S,Padayachee E,Maphumulo S,Govender T,Sayed Y,Maguire G,Lin J,Naicker T,Baijnath S,Gerhardus KH |
Evidence
|
The mutant has five mutations, E35D, two insertions, position 36 (G and S), and D60E.
|
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