HBV Mutation Detail Information

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Mutation Information
Mutation Site D51G
Mutation Type Amino acid level
Gene/Protein/Region Type PreS2
Country Nigeria
Literature Information
PubMed PMID 17503077
Disease HBV associated liver disease
Published Year 2007
Journal Medical microbiology and immunology
Title Hepatitis B virus genotype E surface antigen detection with different immunoassays and diagnostic impact of mutations in the preS/S gene.
Author Olinger CM,Weber B,Otegbayo JA,Ammerlaan W,van der Taelem-Brulé N,Muller CP
Evidence DNA positive samples with no detectable HBsAg or reduced HBsAg detection signals (<75% of mean signal obtained with HBsAg positive samples) revealed several mutations (V14A, F46S, N48T, L49R, I49T, D51G, A53V, P54L, Q82P, F83C, L127P, A184V, T189I, S204N, V224A), mostly outside the a-determinant.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation