HPV Mutation Detail Information

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Mutation Information

Mutation Site	D50E
Mutation Type	Amino acid level
Gene/Protein/Region Type	E1
Amino acid_Mutation	T1014G
Genotype/Subtype	HPV16
Viral Reference	K02718.1
Country	China

Literature Information

PubMed PMID	31341418
Disease	Cervical carcinoma
Published Year	2019
Journal	International journal of medical sciences
Title	Human Papillomavirus Type 16 E1 Mutations Associated with Cervical Cancer in a Han Chinese Population.
Author	Yao Y,Yan Z,Dai S,Li C,Yang L,Liu S,Zhang X,Shi L,Yao Y
Evidence	In the sub-lineage analysis, the differences in the T933A (A23A), T1014G (D50E) and G2160A (R432R) mutations were statistically significant between the case and control groups for the A4 (As) sub-lineage (P<0.05), and the differences in the T2232C (F456F), G2337A (M491I) and A2547G (P561P) mutations were statistically significant between the case and control groups for the A1-A3 (EUR) sub-lineage (P<0.05).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation