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Mutation Information

Mutation Site	D368R
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gp120

Literature Information

PubMed PMID	31126879
Published Year	2019
Journal	Immunity
Title	Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Author	Schoofs T,Barnes CO,Suh-Toma N,Golijanin J,Schommers P,Gruell H,West AP Jr,Bach F,Lee YE,Nogueira L,Georgiev IS,Bailer RT,Czartoski J,Mascola JR,Seaman MS,McElrath MJ,Doria-Rose NA,Klein F,Nussenzweig MC,Bjorkman PJ
Evidence	Mutation of the CD4-binding site (D368R/D368Kgp120, A281Tgp120), the V3 glycan patch (N332A/N332Kgp120), and the V2 apex epitope (N160Kgp120), alone or in combination, did not abrogate SF5 or SF12 binding (Figure 2A).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation