HPV Mutation Detail Information

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Mutation Information
Mutation Site D344E
Mutation Type Amino acid level
Gene/Protein/Region Type E2
Combined Mutation e2.D25N+e2.T135K+e2.R165Q+e2.I210T+e2.E232K+e2.T310K+e2.D344E
Genotype/Subtype HPV16
Country Japan
Literature Information
PubMed PMID 24150786
Disease High grade squamous intraepithelial lesion; Low grade squamous intraepithelial lesion; Cervical carcinoma
Published Year 2014
Journal Journal of medical virology
Title Functional effects of sequence variations in the E6 and E2 genes of human papillomavirus 16 European and Asian variants.
Author Hang D,Gao L,Sun M,Liu Y,Ke Y
Evidence There are seven amino acid substitutions between EUR E2 and As E2, including D25N, T135K, R165Q, I210T, E232K, T310K, and D344E.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation