HIV Mutation Detail Information

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Mutation Information

Literature Information

PubMed PMID	18375964
Published Year	2008
Journal	Bioinformatics (Oxford, England)
Title	Analysis of correlated mutations in HIV-1 protease using spectral clustering.
Author	Liu Y,Eyal E,Bahar I
Evidence	We note in particular that Asp30 and Asn88 exhibit extraordinarily high MI. As shown before (Rhee et al.,), the double mutation D30N and N88D can reduce nelfinavir susceptibility by 50-fold, explaining the selection pressure for their co-variation.

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Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)