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Mutation Information
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Mutation Site
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D25N |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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E6 |
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Genotype/Subtype
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HPV16 |
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Viral Reference
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NC_001526.2
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Country
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China |
Literature Information
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PubMed PMID
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30930693
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Disease
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Cervical intraepithelial neoplasia;
Cervical carcinoma
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Published Year
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2019 |
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Journal
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Cancer cell international |
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Title
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Genetic variations in E6, E7 and the long control region of human papillomavirus type 16 among patients with cervical lesions in Xinjiang, China. |
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Author
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Zhe X,Xin H,Pan Z,Jin F,Zheng W,Li H,Li D,Cao D,Li Y,Zhang C,Fu S,Shao R,Pan Z |
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Evidence
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These caused the amino acid to change from threonine to serine (T22S), aspartic acid to asparagine (D25N), aspartic acid to glutamic acid (D25E), aspartic acid to glutamine (D25Q), isoleucine to arginine (I27R), asparagine to aspartic acid (N58D), asparagine to serine (N58S), aspartic acid to glutamic acid (D64E), leucine to valine (L83V), threonine to lysine (T86K), glutamic acid to aspartic acid (E113D), leucine to phenylalanine (L28F), asparagine to histidine (N29H) and asparagine to serine (N29S), respectively.
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HPV Mutation Detail Information