|
Mutation Information
|
Mutation Site
|
D25N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
Sweden |
Literature Information
|
PubMed PMID
|
12691704
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2003 |
|
Journal
|
Human immunology |
|
Title
|
Association between human papillomavirus 16 E6 variants and human leukocyte antigen class I polymorphism in cervical cancer of Swedish women. |
|
Author
|
Zehbe I,Mytilineos J,Wikström I,Henriksen R,Edler L,Tommasino M |
|
Evidence
|
With regard to the remaining E6 variant postions found together with L83V in four samples (Table 2), only D25N would have an effect in one sample of our study population because glutamic acid in position 25 has a binding score advantage over asparagine when presented within an HLA-A*02 molecule.
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HPV Mutation Detail Information