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Mutation Information
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Mutation Site
|
D25E |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
E6 |
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Amino acid_Mutation
|
T178G |
|
Genotype/Subtype
|
HPV16 |
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Country
|
China |
Literature Information
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PubMed PMID
|
31933750
|
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Disease
|
Low grade squamous intraepithelial lesion
|
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Published Year
|
2019 |
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Journal
|
International journal of clinical and experimental pathology |
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Title
|
Variant sublineages of human papillomavirus type 16 predispose women to persistent infection characterized by a sequence analysis of the E6, L1, and LCR regions. |
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Author
|
Yang B,Zhang L,Zhang A,Zhou A,Yuan J,Wang Y,Sun L,Cao H,Zheng W |
|
Evidence
|
Six single-nucleotide variants were detected in the E6 gene of HPV16: G176A (D25N), T178G (D25E), C335T (H78Y), T350G (L83V), A442C (E113D), and A131C (R10R).
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HPV Mutation Detail Information