|
Mutation Information
|
Mutation Site
|
D25E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E6 |
|
Amino acid_Mutation
|
T178G |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
AAL96630
|
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
31727676
|
|
Clinical information
|
Yes
|
|
Disease
|
Cervical intraepithelial neoplasia
|
|
Published Year
|
2020 |
|
Journal
|
Clinical cancer research : an official journal of the American Association for Cancer Research |
|
Title
|
A Phase II, Prospective, Randomized, Multicenter, Open-Label Study of GX-188E, an HPV DNA Vaccine, in Patients with Cervical Intraepithelial Neoplasia 3. |
|
Author
|
Choi YJ,Hur SY,Kim TJ,Hong SR,Lee JK,Cho CH,Park KS,Woo JW,Sung YC,Suh YS,Park JS |
|
Evidence
|
The HPV sequence analysis revealed that the HPV type 16 E6/E7 variants D25E, V83L, and N29S were inversely associated with histopathological regression at V8.
|
|
|
HPV Mutation Detail Information