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Mutation Information
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Mutation Site
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D25E |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
IN |
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Genotype/Subtype
|
C |
|
Country
|
India |
Literature Information
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PubMed PMID
|
28149058
|
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Disease
|
HIV infection/AIDS
|
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Published Year
|
2016 |
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Journal
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Bioinformation |
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Title
|
Effect of HIV-1 Subtype C integrase mutations implied using molecular modeling and docking data. |
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Author
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Sachithanandham J,Konda Reddy K,Solomon K,David S,Kumar Singh S,Vadhini Ramalingam V,Alexander Pulimood S,Cherian Abraham O,Rupali P,Sridharan G,Kannangai R |
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Evidence
|
The complete predicted study amino acid sequence alignment (up to 288 amino acid residues) showed that the consensus of the study strains was identical to the global subtype C consensus, except at 8 positions (D25E, K42Q, M50I, K110V, V111K, D182I, T218I and R269K). It differed from the global subtype B consensus at 12 positions (R14K, K42Q, V72I, F100Y, L101I, K110V, V111K, V113I, N134G, E167D, D182I and D278A).
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HIV Mutation Detail Information