HIV Mutation Detail Information

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Mutation Information
Mutation Site D253N
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Literature Information
PubMed PMID 19014951
Published Year 2009
Journal Journal of molecular biology
Title Defining the DNA substrate binding sites on HIV-1 integrase.
Author Dolan J,Chen A,Weber IT,Harrison RW,Leis J
Evidence In contrast, Q44N, L68E E69P, D229I S230E, and D253N maintained the ability to cleave the HIV-1 substrate, and gained the ability to cleave the ASV substrates to different extents (Figure 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation