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Mutation Information
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Mutation Site
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D253N |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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IN |
Literature Information
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PubMed PMID
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19014951
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Published Year
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2009 |
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Journal
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Journal of molecular biology |
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Title
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Defining the DNA substrate binding sites on HIV-1 integrase. |
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Author
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Dolan J,Chen A,Weber IT,Harrison RW,Leis J |
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Evidence
|
In contrast, Q44N, L68E E69P, D229I S230E, and D253N maintained the ability to cleave the HIV-1 substrate, and gained the ability to cleave the ASV substrates to different extents (Figure 3).
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HIV Mutation Detail Information