|
Mutation Information
|
Mutation Site
|
D240N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
DNase |
Literature Information
|
PubMed PMID
|
12604820
|
|
Published Year
|
2003 |
|
Journal
|
The Journal of general virology |
|
Title
|
Site-directed mutagenesis in a conserved motif of Epstein-Barr virus DNase that is homologous to the catalytic centre of type II restriction endonucleases. |
|
Author
|
Liu MT,Hu HP,Hsu TY,Chen JY |
|
Evidence
|
Five of the six other acidic residue mutants, E209Q, D213N, D219N, E238Q and D240N, retained their nuclease activities (>75 %) and only the mutant D195N lost nuclease activity (3 %) (Fig. 2F2).
|
|
|
EBV Mutation Detail Information