|
Mutation Information
|
Mutation Site
|
D21N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E7 |
|
Genotype/Subtype
|
HPV16 |
Literature Information
|
PubMed PMID
|
27829177
|
|
Published Year
|
2017 |
|
Journal
|
Virology |
|
Title
|
A naturally occurring variant of HPV-16 E7 exerts increased transforming activity through acquisition of an additional phospho-acceptor site. |
|
Author
|
Zine El Abidine A,Tomaić V,Bel Haj Rhouma R,Massimi P,Guizani I,Boubaker S,Ennaifer E,Banks L |
|
Evidence
|
In contrast, the D21N substitution exhibits a somewhat weaker level of transforming activity, although this does not appear to be statistically significant.
|
|
|
HPV Mutation Detail Information