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Mutation Information
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Mutation Site
|
D192A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Tax |
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Combined Mutation
|
tax.G193S+tax.D192A |
Literature Information
|
PubMed PMID
|
8756622
|
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Published Year
|
1996 |
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Journal
|
Molecular and cellular biology |
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Title
|
Interaction of the human T-cell lymphotropic virus type 1 tax transactivator with transcription factor IIA. |
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Author
|
Clemens KE,Piras G,Radonovich MF,Choi KS,Duvall JF,DeJong J,Roeder R,Brady JN |
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Evidence
|
The M21 (P134A, D135S), M30 (D192A, G193S) M32(Y196A,K197S), and M41(H287A,P288S) mutants were unable to activate either viral LTR (84).
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HTLV1 Mutation Detail Information