HIV Mutation Detail Information

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Mutation Information
Mutation Site D14A
Mutation Type Amino acid level
Gene/Protein/Region Type Vif
Literature Information
PubMed PMID 24418540
Published Year 2014
Journal Virology
Title Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis.
Author Matsui Y,Shindo K,Nagata K,Io K,Tada K,Iwai F,Kobayashi M,Kadowaki N,Harris RS,Takaori-Kondo A
Evidence To test our hypothesis that conserved residues E88 and W89 may be required for CBFβ binding, we generated nine point mutants of Vif, D14A/R15A, W21A, W38A, Y40A, Y69A, G84D, E88A, W89A, and E88A/W89A (Fig. 1A). 

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation