|
Mutation Information
|
Mutation Site
|
D144G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.G145E+s.D144G |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Germany |
Literature Information
|
PubMed PMID
|
17576389
|
|
Disease
|
HBV infection
|
|
Published Year
|
2007 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Long-term surveillance of haematopoietic stem cell recipients with resolved hepatitis B: high risk of viral reactivation even in a recipient with a vaccinated donor. |
|
Author
|
Knöll A,Boehm S,Hahn J,Holler E,Jilg W |
|
Evidence
|
A novel HBV surface mutant (D144G/G145E) was isolated from one recipient of stem cells from a donor vaccinated against HBV. Another surface mutant (P142L/G145R) was detected in a recipient from a non-immune donor.
|
|
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HBV Mutation Detail Information