|
Mutation Information
|
Mutation Site
|
D144E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
rituximab |
|
Country
|
Greece |
Literature Information
|
PubMed PMID
|
23146520
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
Transplantation proceedings |
|
Title
|
Hepatitis B reactivation in a renal transplant patient due to a surface antigen mutant strain: a case report. |
|
Author
|
Fylaktou A,Daoudaki M,Dimou V,Sianou E,Papaventsis D,Mavrovouniotis I,Fouzas I,Papanikolaou V |
|
Evidence
|
Sequence analysis of the surface (S) antigen corresponding to the amino acid residues 101-186 (including the a-determinant region) revealed a genotype D mutant strain, subtype ayw3 with a single amino acid substitution D144E within the S gene.
|
|
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HBV Mutation Detail Information