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Mutation Information
|
Mutation Site
|
D144E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
21671883
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2011 |
|
Journal
|
Current HIV research |
|
Title
|
Detection of hepatitis B virus variants in HBV monoinfected and HBV/HIV coinfected Iranian patients under lamivudine treatment. |
|
Author
|
Aghasadeghi MR,Bahramali G,Sadat SM,Farahani A,Mohraz M,Davar Siadat S,Mostafavi E,Memarnejadian A,Ardestani MS,Vahabpour R,Saraji AA,Delbaz SA |
|
Evidence
|
A significant association between subtypes and mutations of rtS135Y (12.5% ayw2, 81.2% ayw3, 6.3% ayw4, P<0.0001), rtL115Y (85.7% ayw3, 14.28% ayw4, P=0.003),rtM204I (100% ayw2, P=0.03), sD144E (63% ayw2, 87.5%ayw3, 6.3% ayw4, P<0.001) and sS136Y (6.3% ayw2,87.5% ayw3, 6.3% ayw4, P<0.001) was also observed.
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HBV Mutation Detail Information