Mutation Information
Mutation Site
|
D138Y |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Env |
Literature Information
PubMed PMID
|
30566493
|
Published Year
|
2018 |
Journal
|
PloS one |
Title
|
Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant. |
Author
|
Beltran-Pavez C,Ferreira CB,Merino-Mansilla A,Fabra-Garcia A,Casadella M,Noguera-Julian M,Paredes R,Olvera A,Haro I,Brander C,Garcia F,Gatell JM,Yuste E,Sanchez-Merino V |
Evidence
|
Only 3 out of the 37 amino acid replacements observed with a frequency above 5% (D138Y, R503W and K574M) have an acceptability value below 3, supporting the notion of poorly accepted mutations.
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