Mutation Information
Mutation Site
|
D123E |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Nef |
Literature Information
PubMed PMID
|
22651890
|
Published Year
|
2012 |
Journal
|
Retrovirology |
Title
|
Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix. |
Author
|
Kuo LS,Baugh LL,Denial SJ,Watkins RL,Liu M,Garcia JV,Foster JL |
Evidence
|
The Nef mutant with D123E is devoid of MHCI downregulation activity.
|
|
|