Mutation Information
Mutation Site
|
D116N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Literature Information
PubMed PMID
|
32852081
|
Published Year
|
2020 |
Journal
|
The EMBO journal |
Title
|
Disrupting HIV-1 capsid formation causes cGAS sensing of viral DNA. |
Author
|
Sumner RP,Harrison L,Touizer E,Peacock TP,Spencer M,Zuliani-Alvarez L,Towers GJ |
Evidence
|
Mutation D116N of the viral integrase (HIV-1 CA-SP1 INT D116N) impacted neither luciferase induction (Fig 3E) nor CXCL-10 (Fig 3F) secretion.
|
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