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Mutation Information
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Mutation Site
|
C7A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreS |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
24748463
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2014 |
|
Journal
|
Frontiers of medicine |
|
Title
|
Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk. |
|
Author
|
Du Y,Han X,Pu R,Xie J,Zhang Y,Cao G |
|
Evidence
|
However, the TTCA insertion allele of rs3783553 was significantly associated with an increased frequency of HBV C7A mutation compared with homozygous TTCA deletion carriers [(del/ins + ins/ins) vs. del/del, adjusted odds ratio (OR)= 1.48, 95% confidence interval (CI)= 1.09-2.02, P = 0.013].
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HBV Mutation Detail Information