Mutation Information
Mutation Site
|
C76F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Country
|
Nigeria |
Literature Information
PubMed PMID
|
17503077
|
Disease
|
HBV associated liver disease
|
Published Year
|
2007 |
Journal
|
Medical microbiology and immunology |
Title
|
Hepatitis B virus genotype E surface antigen detection with different immunoassays and diagnostic impact of mutations in the preS/S gene. |
Author
|
Olinger CM,Weber B,Otegbayo JA,Ammerlaan W,van der Taelem-Brulé N,Muller CP |
Evidence
|
One strain with the mutation S143T was not detected, by assay A only however mutations outside the “a” determinant (preS2: A53V; S: C76F, F83C and V224A) may be responsible for this “failure”, although also explainable by low HBsAg titers
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