HPV Mutation Detail Information

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Mutation Information
Mutation Site C749T
Mutation Type Nucleotide level
Gene/Protein/Region Type E7
Nucleotide_Mutation S63F
Genotype/Subtype HPV16
Country Romania
Literature Information
PubMed PMID 25143263
Disease Cervical carcinoma; Squamous-cell carcinoma; Cervical intraepithelial neoplasia
Published Year 2014
Journal Archives of virology
Title Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients.
Author Plesa A,Anton G,Iancu IV,Diaconu CC,Huica I,Stanescu AD,Socolov D,Nistor E,Popa E,Stoian M,Botezatu A
Evidence The most prevalent missense mutations in HPV16 E7 (C749T and C790T) were found in 21 cases, leading to the amino acid changes S63F and R77C, respectively.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation