HPV Mutation Detail Information

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Mutation Information
Mutation Site C7294T
Mutation Type Nucleotide level
Gene/Protein/Region Type LCR
Genotype/Subtype HPV16
Viral Reference K02718.1
Country China
Literature Information
PubMed PMID 24099556
Disease Cervical intraepithelial neoplasia; Cervical carcinoma
Published Year 2013
Journal BMC cancer
Title Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China.
Author Sun Z,Lu Z,Liu J,Wang G,Zhou W,Yang L,Liu C,Wang B,Ruan Q
Evidence The EUR lineage variants showed a negative trend of association with the severity of ≥CIN2,3. Among 41 variations found in LCR, 25 (61.0%) were located at the binding sites for transcription factors. Occurrence of ≥CIN2,3 was significantly associated with the mutations of R10G/L83V in E6 and the C7294T co-variation in LCR, after adjusting for ages of infected patients.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation