Mutation Information
Mutation Site
|
C6795T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
Gp120 |
Nucleotide_Mutation
|
T192M |
Literature Information
PubMed PMID
|
28100611
|
Published Year
|
2017 |
Journal
|
Journal of virology |
Title
|
The Envelope Gene of Transmitted HIV-1 Resists a Late Interferon Gamma-Induced Block. |
Author
|
Rihn SJ,Foster TL,Busnadiego I,Aziz MA,Hughes J,Neil SJD,Wilson SJ |
Evidence
|
Perhaps more importantly, of the three total polymorphisms that were detected in the swarm propagated in the presence of IFN-gamma, only one was selected to uniformity (Fig. 9B and C). This single transition, C6795T, encodes a nonsynonymous substitution in variable region 2 (V2) of the envelope glycoprotein (Env), T192M.
|
|
|