HPV Mutation Detail Information

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Mutation Information
Mutation Site C6689A
Mutation Type Nucleotide level
Gene/Protein/Region Type L1
Nucleotide_Mutation T375N
Genotype/Subtype HPV58
Viral Reference D90400.1
Country Brazil
Literature Information
PubMed PMID 25793187
Disease Low grade squamous intraepithelial lesion; High grade squamous intraepithelial lesion
Published Year 2015
Journal BioMed research international
Title Prevalence of human papillomavirus variants and genetic diversity in the L1 gene and long control region of HPV16, HPV31, and HPV58 found in North-East Brazil.
Author Gurgel AP,Chagas BS,do Amaral CM,Nascimento KC,Leal LR,Silva Neto Jda C,Cartaxo Muniz MT,de Freitas AC
Evidence The most common are nucleotide changes were A6540G (I335M), C6828A (N422D), A6014C (L150F), G5994A (V144I), A6799G (I412V), G6823A (D420N), and C6689A (T375N); these are either located in the external loop (DE/HI loop) or alpha helix (H2 and H3) regions.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation