HPV Mutation Detail Information

> C6460G Search Result


Mutation Information
Mutation Site C6460G
Mutation Type Nucleotide level
Gene/Protein/Region Type L1
Nucleotide_Mutation P344R
Genotype/Subtype HPV18
Viral Reference NC_001357.1
Country China
Literature Information
PubMed PMID 23451059
Disease Cervical carcinoma
Published Year 2013
Journal PloS one
Title Sequence variation analysis of HPV-18 isolates in southwest China.
Author Shen M,Ding X,Li T,Chen G,Zhou X
Evidence DNA sequence analysis of the HPV-18 L1 region revealed six variations: a G to A transition at nt5503, leading to a R25Q AA substitution (n = 23, 41.1%) (Fig. 1I); a C to G transversion at nt5701 with an AA change of P91R (n = 23, 41.1%) (Fig. 1J); a C to G transversion at nt6460 with an AA change of P344R (n = 24, 42.9%) (Fig. 1K); a C to G transversion at nt6625 with an AA change of P399R (n = 25, 44.6%) (Fig. 1L); a C to G transversion at nt6842 with an AA change of P471R (n = 23, 41.1%) (Fig. 1M); and G to A transition at nt6906 with an AA change of D493N (n = 12, 21.4%) (Fig. 1N).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation